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49ers lose 17-10: 4th down failures and penalties define Trey Lance’s first start

The 49ers looked to knock off the undefeated Cardinals in rookie quarterback Trey Lance’s first career NFL start. Instead, they fell to the NFC West division leader 17-10, unable to take advantage of a fantastic defensive performance.

Daniel Brunskill and Mike McGlinchey let two pass rushers quickly by them on the first play of the game, putting Lance in a terrible position. Then, the rookie sprinted forward in the pocket and recorded a 14-yard run. It was an early example of how he can help the 49ers offense reach another level.

The next play was a nice touch pass to an open Kyle Juszczyk and the 49ers were moving it downfield.