The Buffalo Bills were entering this game knowing they would be without two key pieces of their offense as running back Zack Moss and tight end Dawson Knox were ruled out Friday due to injuries.
The rookie running back suffered a toe injury and his absence now means that running back Devin Singletary should see a significant increase in his workload in this game. As for the tight end, it will be veteran Tyler Kroft stepping into the starting lineup for Knox.
The good news though is linebackers Tremaine Edmunds and Matt Milano are both returning this week.