The Hilltoppers (11-8) have won eight of their last 10 matchups against the Governors (9-9). WKU has won all four of its midweek games this year.
Right-hander Cody Coll (0-0, 4.11 ERA) will get the start for the Tops. Austin Peay will counter with righty Caleb Powell (1-1, 4.50).
APSU enters the game tied for fourth in the NCAA in home runs (27) and in the top 50 in team batting average (.304).