West Ham forward Michail Antonio, who tested positive for Covid-19 last week, is hoping for the all-clear to return.
Vladimir Coufal is available after serving a one-match ban, while Aaron Cresswell could be fit.
Southampton midfielder Stuart Armstrong might feature for the first time since the start of November after recovering from a calf injury.
Che Adams, Adam Armstrong and Fraser Forster have all overcome injury problems.
LAWRO'S PREDICTION
West Ham have hit a bit of a sticky patch and it's no surprise it has coincided with them suffering a few injuries to key players at a time they have had a lot of games.