West Ham goalkeepers Lukasz Fabianski and Darren Randolph are both nursing injuries.
Leeds will assess Pascal Struijk, who was forced off in the home defeat by Aston Villa, plus several players who are nearing a return to full fitness.
Rodrigo, Gaetano Berardi and Ian Poveda all played for the development side on Friday, but Kalvin Phillips missed out.
LAWRO'S PREDICTION
Leeds are very up and down at the moment - they are a bit like Aston Villa in that they are hard to predict.
West Ham have been far more consistent, which is why they are in the race for the top four.