Everton forwards Dominic Calvert-Lewin and Richarlison will miss a sixth and fifth game respectively due to injury.
Seamus Coleman, Alex Iwobi and Lucas Digne have all returned to training and will be assessed.
West Ham United could welcome back Ryan Fredericks, who has missed the past three matches with a groin problem.
Fellow full-back Vladimir Coufal will be monitored after he missed the Czech Republic's international fixtures because of a groin injury.
LAWRO'S PREDICTION
Everton have made an excellent start to the season but they might find it hard going against West Ham - they certainly won't get the wide open spaces they enjoyed in their draw with Manchester United.