Manchester United will host West Ham United in the Carabao Cup third round.
The tie will see Hammers boss David Moyes return to the club that sacked him in 2014 after 10 months in charge.
Four-time defending champions Manchester City will host League One side Wycombe Wanderers while Nuno Espirito Santo returns to his former club as Tottenham face Wolves.
Chelsea host Aston Villa and Norwich City welcome Liverpool in the other all-Premier League ties.
The games will take place in the week commencing 20 September.
Pep Guardiola's side have dominated the competition in recent years, winning it in each of the last four seasons including last year when they beat Tottenham 1-0 at Wembley.