Everton face a selection problem at centre back with Jarrad Branthwaite sustaining an ankle injury in the Carabao Cup win over Salford City.
The 18-year-old looks set to join Mason Holgate, who has a toe injury, on the sidelines.
West Brom, like Everton, made 10 changes for their midweek cup win over Harrogate Town.
New signing Branislav Ivanovic was not among those involved on Wednesday but he could feature against the Toffees.
MATCH FACTS
Head-to-head
- Everton have only lost one of the past 11 league meetings, winning five and drawing five.