West Brom boss Sam Allardyce says football needs a break after the Premier League returned its highest number of positive coronavirus results in a single round of tests this season.
On Tuesday, the latest round of Premier League testing found 18 people had the virus.
New coronavirus cases at Fulham mean their Premier League match at Tottenham on Wednesday is in doubt.
"I'm very concerned for myself and football in general," said Allardyce.
Sheffield United have confirmed they had "numerous positive tests" in the latest round of testing.
On Monday, Manchester City's Premier League match at Everton was postponed four hours before kick-off because of a coronavirus outbreak.