Ki-Jana Hoever has been ruled out with the hamstring injury that prompted his first-half substitution against Crystal Palace.
With Nelson Semedo unavailable with a similar issue, Jonny Otto could make his first start for a year.
Watford remain without Ismaila Sarr but team-mate Joshua King will be assessed. Both missed the game against Arsenal on Sunday because of hamstring injuries.
William Troost-Ekong is available after overcoming a muscle strain.
MATCH FACTS
Head-to-head
- Wolves won 2-0 in the reverse fixture in September and are aiming for a first Premier League double over Watford.