Chat Sports
Virginia Tech news

Fansided · Nov 1, 2025

Virginia Tech vs. Louisville: Final odds and prediction

Vanderbilt v Virginia Tech | Ryan Hunt/GettyImagesComing off a thrilling 42-34 double overtime win over California last Friday night at Lane Stadium, the Virginia Tech football team will look to pull off an upset on Saturday afternoon when Louisville enters Blacksburg as a double-digit favorite.

Virginia Tech will need to establish the run if they are going to hang around with the Cardinals, who are still in the thick of the ACC race for a spot in the ACC Championship Game in December in Charlotte. Let's take a look at the latest odds and give a prediction for the game.

Virginia Tech vs. Louisville: Odds

Moneyline

Louisville -425

Virginia Tech +330

Louisville -10.5 (-110)

Virginia Tech +10.5 (-110)

Full story at Fansided

Chat Sports on YouTube

Chat Sports TV

NFL Daily | NBA Now | CFB Now

Subscribe

More Virginia Tech news

Highlights vs. Iowa (11/10/26) Hokies Official Site · 1h +1 more source Hokies secure overtime win versus Iowa 93-88 Hokies Official Site · 6h Instant Takeaways From Virginia Tech's 93-88 Overtime Triumph Over Iowa Virginia Tech Hokies On SI · 6h Virginia Tech basketball: Hokies pick up huge early-season win over Iowa 93-88 Gobbler Country · 7h 3 winners and 2 losers from Virginia Tech's massive statement overtime win over Iowa Fansided · 7h Dan Lanning lurking in the woods to flip 4-star Virginia Tech 2027 commit Fansided · 11h All Virginia Tech news