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Vegas Football Odds: Virginia opens as 3.5-point favorites over Louisville

While the Virginia Cavaliers are coming off a strong 45-31 win over the Ohio, the Louisville Cardinals needed a big fourth quarter rally and a little bit of luck to defeat 0-3 Western Kentucky. As Virginia hosts the Cardinals on Saturday in Scott Stadium, Las Vegas oddsmakers are saying that the Hoos are favored by 3.5 points over the Cards.

On the season, Virginia is a perfect 3-0 against the spread.

Virginia Football Against the Spread

Date Team Closing Odds Final Result vs.