After opening the season with two games against top-20 teams, the Hoos finally get a breather this week. This week's opponent is ranked 25th. In the FCS poll. William and Mary are a solid FCS team, and they opened their season with a 34-7 road win against Lafayette College in Pennsylvania. (In case you were wondering, Lafayette isn't very good.)
The Hoos first played W&M in 1908, winning 11-0. All time, the Hoos are 27-6-1 in this series. The low point might be the 1959 matchup that the Indians (their nickname from 1916-1977) won 37-0, playing in Charlottesville.