Each Friday on ESPN Insider, ESPN Chalk college basketball handicapper Andrew Lange will give you against-the-spread picks on the biggest games of the weekend. Here's a look at Louisville-Virginia, Iowa State-Kansas and other intriguing Saturday matchups.
4 pm ET, ESPN
Projected line: Kansas -10
Projected total: 159
With 10 straight wins, nine out of 10 pointspread covers and another Big 12 title, no team is riding as high as the Jayhawks heading into Saturday's regular-season finale against Iowa State. Oh, and it's also senior night as well as a "revenge" spot after the Cyclones romped in Ames, 85-72; that was Kansas' last loss, way back on Jan.