USC seized the momentum in the first half thanks to two Cameron Smith interceptions of Utah QB Travis Wilson, the second of which he returned 53 yards for a touchdown to give the Trojans a 28-14 lead.
Smith would add another interception in the second half to finish with three on the night.
QB Cody Kessler was efficient all night long, going 21-of-28 for 264 yards -- eight of those completions to budding star WR JuJu Smith-Schuster for 143 yards and a touchdown. He also rushed for a score, backing up TD runs by Ronald Jones II, Justin Davis and fullback Soma Vainuku.
That was more than enough to keep the Utes (6-1, 3-1 Pac-12) at bay in a frustrating night for the formerly undefeated squad, sending Utah back into the one-loss pack while snapping a two-game skid for USC (4-3, 2-2) and handing interim head coach Clay Helton a win in his first game at the Coliseum.
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