The 10-time Spanish League champions beat the MLS All-Stars 3-0 Wednesday night, with Marcos Llorente, Joao Felix, Diego Costa scoring goals to pace the rout before a sellout crowd of 25,527.
The loss was the fourth straight for MLS in its annual All-Star game, which matches the league's top players against international competition.
"It was an interesting game. It was competitive," Simeone said through an interpreter. "In the second half, we were able to do things that allowed us to win."
Llorente scored in the 43rd minute and Feliz and Costa came off the bench to score late goals in the rain-delayed match away before a sellout crowd of 25,527.