Pep Guardiola quickly turned his focus towards Manchester United after Manchester City thrashed Fulham 4-0 in the FA Cup fourth round.
The game as a contest was effectively over inside the opening eight minutes, with visiting captain Tim Ream dismissed for a foul on Gabriel Jesus and Ilkay Gundogan converting the consequent penalty.
Bernardo Silva doubled the hosts' and holders' advantage before the interval at the Etihad Stadium, with Jesus' quickfire second-half double putting the gloss on things.
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Next up for City is the visit of bitter rivals United in the second leg of their Carabao Cup semi-final, with Guardiola's side boasting a 3-1 aggregate lead.