The Manchester City star is continuing his recovery from a fractured nose and eye socket
Belgium have confirmed that Kevin De Bruyne and Axel Witsel will both miss the team's Euro 2020 opener against Russia on Saturday.
De Bruyne is still recovering from a fractured nose and eye socket he suffered in the Champions League final with Manchester City, which required a minor operation.
Witsel, meanwhile, has been out since January after suffering a torn Achilles with Borussia Dortmund.