Wolves are without defender Hugo Bueno, who injured his hamstring in the midweek defeat at Liverpool.
Forward Matheus Cunha could return from the ankle injury which saw him stretchered off at Fulham last weekend.
Tottenham wing-back Emerson Royal is likely to be recalled after missing the FA Cup loss to Sheffield United with a knee issue.
Harry Kane, Clement Lenglet and Cristian Romero are expected to start after they were benched on Wednesday.
CHRIS SUTTON'S PREDICTION
Tottenham have been so inconsistent all season that I don't think any result for them is a huge shock, whether it be them beating Manchester City or losing to Championship side Sheffield United in the FA Cup.