Tottenham paid the price for leaving their star players at home as Dutch side Vitesse Arnhem earned a deserved win in the Europa Conference League.
Vitesse left-sided midfielder Maximilian Wittek crisply converted a volley from the edge of the area, dealing a blow to the visitors' hopes of progressing comfortably from Group G.
With key players including Harry Kane and Son Heung-min rested, Spurs fielded a different starting XI to the one who beat Newcastle in the Premier League on Sunday and they lacked rhythm in a poor performance.
The Dutch side, who finished fourth in the Eredivisie last season, created the better opportunities and delighted a sell-out crowd when Wittek finally made their dominance count.