Tottenham Hotspur and Borussia Dortmund return to the Champions League arena on Wednesday night in one of a number of eye-catching group stage fixtures.
With defending champions Real Madrid also in the group, this fixture at Wembley could already prove crucial in deciding the outcome of the group.
We take a look at the key factors where the match could be won and lost.
DORTMUND FACE INJURY CRISIS
Dortmund arrive in London as a depleted force, with nine first-team squad members out through injury.