Tottenham will be without Giovani lo Celso when they host Dinamo Zagreb in the first leg of their Europa League last-16 tie on Thursday.
The Argentine midfielder was closing in on a return from a hamstring injury but misses out with a back problem.
Dinamo are likely to be without right-back Sadegh Moharrami, who has been injured since January.
However, midfielder Bartol Franjic returns from suspension and is in contention to start.
Aside from Lo Celso, Joe Rodon is Tottenham's only absentee with the defender not registered for the competition.
Manager Jose Mourinho has indicated he will make several changes to his starting XI as Spurs seek their fifth consecutive victory in all competitions.