Tottenham welcome Son Heung-min and Yves Bissouma back to the squad following their return from international duty.
Midfielder Giovani Lo Celso is back in training following a thigh injury.
Brighton may have Kaoru Mitoma available following his Asian Cup campaign but are without Simon Adingra, who will be involved in the Africa Cup of Nations final for Ivory Coast.
Julio Enciso, Solly March, James Milner and Joel Veltman all remain out.
MATCH FACTS
Head-to-head
- Tottenham have won six of their past seven home league games against Brighton, the exception being a 1-0 defeat in April 2022.