Tottenham wing-back Matt Doherty is out for the season with a knee injury sustained during last Saturday's win at Aston Villa.
Oliver Skipp is still struggling with a groin issue, while Japhet Tanganga is the only other long-term absentee.
Brighton have no fresh injury concerns and Graham Potter could name the same side that beat Arsenal last weekend.
Adam Webster returned as a substitute for that match and is pushing for a first start in two months.
LAWRO'S PREDICTION
Brighton got a brilliant win at Arsenal last weekend, but it is hard to see a repeat of that result on their return to north London because Tottenham are absolutely flying at the moment.