Tottenham midfielder Giovani Lo Celso flew to Spain on Friday night ahead of joining Villarreal on a season loan.
There is no option to buy in the deal and the 26-year-old can be recalled by Tottenham in January.
He is one of a number of players Antonio Conte is trying to offload, along with Sergio Reguilon, Tanguy Ndombele, and Harry Winks.
Spurs are thought to have been close to agreeing moves away for all four, but have found difficulty in completing those deals due to hesitancy from individuals to commit to moves.