Harry Winks and Harry Maguire are set to make their England debuts in Lithuania on Sunday night.
Gareth Southgate will ring the changes from the team that started against Slovenia on Thursday night.
Tottenham midfielder Winks and Leicester defender Maguire are in line to make their international debuts from the start, while Aaron Cresswell is poised for his full England debut.
Dele Alli is expected to return to the starting XI after his suspension, while Harry Kane has told Southgate he does not want to be rested for England’s final World Cup qualifier.