Staked to a lead, Jose Urquidy started well, but that didn’t last long.
He struck out Joc Pederson on four pitches and retired Adam Duvall on a fly ball to center.
The third batter of the inning was Travis d’Arnaud, who promptly tied the game with a 375-foot homer to left.
Dansby Swanson singled to left, but Urquidy got out of the inning when Eddie Rosario, swinging at the first pitch he saw, lined out to first.
The Astros are the first team on the board.
Jose Altuve, who struggled badly in Game 1, opened this game with a double to left off Max Fried.