Who will start and who will sit? Stephania Bell combed the injury reports to let you know whom you can trust for your lineups this week.
To help you set your lineups and avoid starting a player who won't take the field, we will post fantasy-relevant updates and analysis here as NFL teams release their inactive lists, typically around 90 minutes before kickoff. Any rankings cited in this column come from our ESPN Fantasy staff ranks.
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Ruled out before Sunday
Offense: RB Devonta Freeman (knee), RB Marlon Mack (hamstring), TE Jack Doyle (hip), RB Darren Sproles (hamstring), RB Jay Ajayi (back), RB Dalvin Cook (hamstring), RB Joe Mixon (knee/meniscus), TE Greg Olsen (foot), K Greg Zuerlein (groin), WR Doug Baldwin (knee/MCL)
Defense: DT Tyeler Davison (foot), LB Manti Te'o (knee), DE Takkarist McKinley (groin), CB Kevin King (groin), DT Denico Autry (ankle), DE Everson Griffen (knee), CB Marcus Sherels (ribs), DT P.