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Week 15 NFL Odds and Best Bets

There’s 16 games across the NFL schedule in Week 15 but only 10 are scheduled for the “main slate” of 1 p.m. ET, 4:05 p.m. ET and 4:25 pm ET. Those 10 matchups are also what’s featured in SI Sportsbook’s Perfect 10 contest. With a free entry, eligible participants pick 10 games against the spread for a chance to win $10,000.

Of those 10 games, four feature home underdogs with the Texans, Bears, Jaguars and yes, even Tom Brady and the Buccaneers all spotted points in the comfortable confines of their own stadium.