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Week 12 Waiver Wire: Fantasy Football's Top Pickups and Breakout Candidates

A notable injury at running back will shake up fantasy football lineups for Week 12, so managers must find a potential replacement for the short-term future.

Indianapolis Colts running back Marlon Mack ran all over the Jacksonville Jaguars defense Sunday, logging 14 rush attempts for 109 yards, but he exited the game with a significant injury. For now, the coaching staff seems to have a backup in place to handle the majority carries. Who's in line for an expanded role in Week 12?

Even in a loss, the Miami Dolphins have some continuity that should appeal to fantasy owners.