Veteran quarterback Tyrod Taylor suffered a hamstring injury midway through the Texans' contest with the Browns on Sunday.
He has been ruled out for the remainder of the game, the team announced.
Taylor, 32, appeared to suffer the injury on a scramble that ended up in a touchdown with 8:32 to go in the second quarter. Taylor seemed to pull up at the end of his run and took a knee in the end zone.
While he finished off the rest of the first half, Taylor did not return in the second half. In his place, 2020 third-round pick Davis Mills was thrust into action.