A key AFC South matchup will take place in Indianapolis on Sunday when the Colts (4-5) host the Tennessee Titans (5-4) as small home favorites at sportsbooks. The Colts have won three straight games following a four-game losing streak while the Titans have won two in a row to pull within one game of first place in the division.
NFL point spread: The Colts opened as three-point favorites; the total was 49 early in the week, according to sportsbooks monitored by OddsShark. (Line updates and matchup report)
NFL betting pick, via OddsShark computer: 27.