The 49ers return to the United States after a strong Week 11 showing on Monday Night in Mexico, where they defeated the Cardinals 38-10, earning them their third straight victory. Their Week 12 opponents, the Saints, also won in Week 11, ending their two-game losing streak. Despite their successes last week, San Francisco and New Orleans look like two very different teams at this point in the season. The 49ers (6-4) are in first place in the NFC West and appear to be a strong Super Bowl contender, while the Saints (4-7) are third in the NFC South and have four teams ahead of them for the last NFC wild-card spot.
Saints-49ers Week 12 Odds, Lines and Spread
