running back reportedly isn't expected to play in Thursday night's Week 8 game against the Atlanta Falcons.
Tom Pelissero of the NFL Network reported the update.
McCaffrey returned to practice this week as he gets closer to coming back from an ankle injury that landed him on injured reserve after Week 2. His next chance to play will come Nov. 8 against the Kansas City Chiefs.
The 24-year-old has amassed 223 total yards and four touchdowns in two games for the 3-4 Panthers under first-year head coach Matt Rhule.
The Stanford product is in his fourth NFL season.