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Yahoo Sports · May 13, 2025

Predicting 5 primetime games on the 49ers 2025 schedule

The San Francisco 49ers' schedule will be announced Wednesday, and the expectation is a full slate of primetime games for one of the NFL's premier franchises.

A last place schedule and games against the AFC and NFC South typically wouldn't help the 49ers snag those primetime matchups, but there are a handful of matchups that jump out as potential national TV offerings.

While we don't know the order of the games just yet, we can start sifting through their opponents and picking out the games we think will either be on Thursday, Sunday or Monday night. Here are the five games we're predicting to land in a primetime slot:

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