The fierce in-state rivalry revs back up for the first time since 2000.
On Saturday, Penn State and Pitt will meet for the 97th time in the Keystone Classic at Heinz Field.
Both teams have feature running backs in James Conner (Pitt) and Saquon Barkley (Penn State), so the game could easily turn into a battle on the ground.
Here's how you can watch Penn State-Pitt, and the keys to victory for both teams.
Penn State at Pitt
When: Saturday, Sept. 10, 12:00 p.m.
Where: Heinz Field, Pittsburgh, Penn.