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Notre Dame-USC Week 13 College Football Odds, Lines, Spread and Bet

USC took a big step toward the College Football Playoff by beating UCLA last week, but the competition rises another level this week with a resurgent Notre Dame coming to the Coliseum. The Trojans have an explosive offense but the Fighting Irish have been a top 10 defense nationally in the month of November in terms of yards allowed.

Notre Dame vs. USC Odds

Spread: ND +5.5 (-110) | USC -5.5 (-118)
Moneyline: ND (+170 | USC (-250)
Total: 64 - Over (-118) | Under (-110)
Game Info: Saturday, Nov.