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NFL Week 4 Picks: Game Odds, Props, Lines and Over-Under Predictions

The San Francisco 49ers battled through a litany of injury issues to win back-to-back games at MetLife Stadium.

In Week 4, the 49ers return back home for a Sunday night showcase against one of the worst teams in the , the Philadelphia Eagles.

The 49ers sit as a seven-point favorite at the moment. That number may be easy to clear based off their last two performances.

One of the largest spreads of the Week 4 slate comes from another NFC West versus NFC East game on the west coast.

Sean McVay's Los Angeles Rams are one of two 13-point favorites in Week 4 for their home clash with the New York Giants.