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NFL Week 4 Picks: Game Odds, Props, Lines and Over-Under Predictions

On paper, the Week 4 matchups in the NFL don't stand out right away.

But if you're looking for good spots to bet money, there's plenty of them with a few lopsided spreads in play Sunday.

In addition to some large spreads, there are four over/under lines set over 50, including Kansas City's Monday trip to Denver.

If you're bold enough to rely on underdogs in Week 4, there are plenty of intriguing options from a 3-0 team to franchises putting trust in their first-year quarterbacks.

NFL Week 4 Schedule and Odds

Thursday, September 27

Minnesota at Los Angeles Rams (-7) (Over/Under: 49.