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N.F.L. Week 2 Predictions: Our Picks Against the Spread

Jeff Roberson/Associated Press

After several major upsets last week in N.F.L., the bar for Week 2 to compete is set awfully high. Were Jacksonville and Washington one-week wonders? Can Chicago replicate its wild fourth quarter for an entire game? Exactly how worried should San Francisco be about the team’s injuries and a home loss to Arizona? If we are lucky, chaos will reign and we will still be searching for answers heading into Week 3.

Here is a look at N.F.L. Week 2, with all picks made against the point spread.

Last week’s record: 8-8

Sunday’s Best Games

Chiefs at Chargers, 4:25 p.