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NFL Week 1: What to watch as 2022 season kicks off

The NFL's 2022 season finally kicks off this week. Here are the Week 1 games and storylines, as well as how to watch on the new NFL+ streaming service, where you can catch all games in your local market and prime time games during the regular season. (All times ET.)

Thursday, Sept. 8

Buffalo Bills at Los Angeles Rams, 8:20 p.m.

Sean McVay, Matthew Stafford and the Rams open defense of their Super Bowl title against Josh Allen and the Bills, who are the betting favorites to win this year's edition.