If you take a look around the NFL in Week 10, you'll notice that eight quarterbacks did not lead their team out of the tunnel in Week 1: Drew Stanton, Ryan Fitzpatrick, Brett Hundley, Mitchell Trubisky, Jacoby Brissett, Case Keenum, C.J. Beathard and Brock Osweiler.
Whether it's due to injury or ineffectiveness, many players are receiving unforeseen opportunities at a crucial time in the NFL calendar, when the playoff picture begins to take some shape.
The performances of these backups-turned-starters will determine a large portion of the playoff landscape this year. Until then, here's a look at all of the Week 10 matchups, with picks against the spread.