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New England Patriots vs. Detroit Lions Odds, Analysis, NFL Betting Pick

The New England Patriots (1-1) will look to bounce back from a rare loss when they visit a familiar face in Detroit against the Lions (0-2) as solid road favorites at sportsbooks for the Week 3 Sunday night game.

The Patriots fell to the Jacksonville Jaguars 31-20 last week for the first time ever with Tom Brady under center, and next he will face his former defensive coordinator Matt Patricia, now the head coach of the Lions.

NFL point spread: The Patriots opened as seven-point favorites; the total was 50 early in the week, according to sportsbooks monitored by OddsShark.