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Los Angeles Rams vs. Indianapolis Colts NFL Week 2 Odds, Plays and Insights

Sep 12, 2021; Inglewood, California, USA; Los Angeles Rams head coach Sean McVay smiles after a touchdown pass from quarterback Matthew Stafford (9) to wide receiver Robert Woods (2) in the fourth quarter against the Chicago Bears at SoFi Stadium. Mandatory Credit: Jayne Kamin-Oncea-USA TODAY Sports

Oddsmakers give the Los Angeles Rams (1-0) the advantage on Sunday, September 19, 2021 against the Indianapolis Colts (0-1). Los Angeles is favored by 3.5 points. The point total for the contest is set at 48.

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