The battle of Southern California will take place at Los Angeles Memorial Coliseum on Sunday when the Rams (2-0) host the Chargers (1-1) as solid home favorites at sportsbooks.
Both teams have been impressive so far this season, especially last week when they defeated their respective opponents by a combined score of 65-20.
NFL point spread: The Rams opened as seven-point favorites; the total was 48.5 early in the week, according to sportsbooks monitored by OddsShark. (Line updates and matchup report)
NFL betting pick, via OddsShark computer: 23.