The Lions (7-7) head to Charlotte to face the Panthers (5-9) for a Week 16 matchup Saturday. The game total has been set at 44.5 with the Lions favored by three.
The Lions are riding a three-game win streak and have won six of their last seven. They are now in second place in the NFC North with two more wins than the Packers, who they beat in Week 8 when they started their hot streak.
This is the first time Detroit is a road favorite this season.
Quarterback Jared Goff has no shortage of weapons with Amon-Ra St.