Philadelphia Eagles head coach Doug Pederson announced Friday that defensive tackle Fletcher Cox will miss his second straight game Sunday against the Arizona Cardinals with a calf injury, according to the Philadelphia Inquirer's Jeff McLane.
Cox initially suffered the injury in Week 3 against the New York Giants.
Cox reached his second straight Pro Bowl in 2016 after finishing with 6.5 sacks and 43 combined tackles. He helped anchor a defensive line that ranked second in adjusted line yards and 11th in adjusted sack rate, per Football Outsiders.