The will be without two wide receivers for Thursday's game against the Detroit Lions.
Per NFL Network's Ian Rapoport, Kenny Stills and Randall Cobb have been ruled out.
According to Houston's official injury report, Cobb is dealing with a toe injury, while Stills has a quadricep injury.
Rapoport noted that Cobb "will miss several more games."
Stills was a late addition to Houston's roster last season when he came over on Aug. 31 as part of the trade with the Miami Dolphins for Laremy Tunsil.