San Francisco 49ers tight end George Kittle is expected to miss Sunday's season opener against the Chicago Bears with a groin injury, Eric Branch of the San Francisco Chronicle.
Kittle suffered the injury during practice on Monday and had been sidelined since.
However, there was some optimism that he would play after he told reporters Friday he was feeling "significantly better" than he did earlier in the week and would do everything possible to play against the Bears.
Kittle previously missed 11 games over the past two seasons due to injuries and hasn't played a full season since 2018.