NFL Network's Ian Rapoport reported he's been diagnosed with a bone contusion.
Freeman, 26, was injured in last week's loss to the Pittsburgh Steelers. He finished with eight carries for 32 yards.
In his fifth NFL season, Freeman has dealt with injuries throughout 2018. He missed three games with a knee contusion earlier this year. Ito Smith took over Tevin Coleman's role as a backup and will likely get carries in the event Freeman misses time.